The present invention provides a mahonia extract, which is obtained by extracting mahonia using ethanol. The mahonia extract may have the effects of antioxidation, pain relief, anti-inflammation, and liver protection. Moreover, the present invention also provides a preparation method of the mahonia extract and an application thereof. The application includes the application for preparation of medicine for antioxidation, pain relief, anti-inflammation and liver protection.本發明提供一種十大功勞(Mahonia)萃取物,係藉由乙醇萃取十大功勞而得。該十大功勞萃取物具有抗氧化、鎮痛、抗發炎及護肝之功效。此外,本發明亦提供該十大功勞萃取物之製備方法以及其用途,該用途包含用於製備抗氧化、鎮痛、抗發炎及護肝之醫藥的用途。
