process and device for sterile hose connection. The invention relates to a process for sterile hose connection with the steps: a) providing a first and second hose (1a, 1b); b) heating a separation region of the first and second hoses (1a, 1b) using heating means; c) mechanical separation of both hoses (1a, 1b) by applying a tensile and / or shear force on the hoses, so that both hoses (1a, 1b) are respectively separated in the separation region. heated in a first and a second segment in the separation region heated in a first and a second segment in the separation region heated in a first and a second hose segment (100a, 100b, 101a, 101b); and d) after splitting the flexible tubes (1a, 1b) producing a mechanical contact of the end (1001a) of the first flexible tube segment (100a) of the first flexible tube (1a) formed by separating the first flexible tube with the end (1001b). ) of the first flexible tube segment (100b) of the second flexible tube (1b) formed by the separation of the second flexible tube (1b), whereby e) mechanical contact production occurs such that the ends (1001a, 1001b) of the Hose segments (100a, 100b) due to heating according to step b) still exhibit such temperature when they come into mechanical contact with each other so that they establish a positive bonding connection with each other without further heating after separation. The invention also relates to a device for sterile hose connection.processo e dispositivo para conexão estéril de tubos flexíveis. a invenção refere-se a um processo para conexão estéril de tubos flexíveis com as etapas: a) disponibilização de um primeiro e um segundo tubo flexível (1a, 1b); b) aquecimento de uma região de separação do primeiro e do segundo tubo flexível (1a, 1b) com emprego de meios de aquecimento; c) separação mecânica de ambos os tubos flexíveis (1a, 1b) mediante aplicação de uma força de tração e/ou de cisalhamento sobre os tubos flexíveis, de modo que ambos os tubos flexíveis (1a, 1b) são respec