PROBLEM TO BE SOLVED: To provide a method and composition for treating psoriasis and other skin disorders.SOLUTION: A composition for topical administration comprises: (a) 25% or more of a sterol ester, based upon the weight of the composition less any solvent that may be present, with a boiling point of 150°C or less; (b) a penetration enhancer; and optionally (c) further additives selected from the group consisting of solvents, film forming/polymeric agents, viscosity increasing agents, emulsifiers, antioxidants, pH adjusting agents, preservatives, vitamins, propellants and mixtures of them.SELECTED DRAWING: NoneCOPYRIGHT: (C)2019,JPO&INPIT【課題】乾癬及び他の皮膚障害を治療するための方法及び組成物の提供。【解決手段】局所投与のための組成物であって、(a)沸点が150℃以下である、存在し得る全ての溶媒を除外した前記組成物の重量に基づいて25%以上のステロールエステル、(b)浸透促進剤、及び、(c)任意に、溶媒、被膜形成/高分子剤、粘度増強剤、乳化剤、抗酸化剤、pH調整剤、保存料、ビタミン類、噴射剤及びこれらの混合物からなる群より選ばれる追加的添加剤、を含有する、組成物。【選択図】なし