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PIPERAZINO[1,2-A]INDOL-1-ONES AND [1,4]DIAZEPINO[1,2-A]INDOL-1-ONE
专利权人:
F. HOFFMANN-LA ROCHE AG
发明人:
CECCARELLI, SIMONA M.,JAGASIA, RAVI,JAKOB-ROETNE, ROLAND,WICHMANN, JUERGEN
申请号:
SG11201408529V
公开号:
SG11201408529VA
申请日:
2013.08.05
申请国别(地区):
SG
年份:
2015
代理人:
摘要:
The present invention relates to compounds of general formula I or pharmaceutically acceptable salts thereof, wherein R1, R2, R3, X, R and n are as defined herein. The compounds may be used for the treatment of schizophrenia, obsessive-compulsive personality disorder, major depression, bipolar disorders, anxiety disorders, normal aging, epilepsy, retinal degeneration, traumatic brain injury, spinal cord injury, post-traumatic stress disorder, panic disorder, Parkinson's disease, dementia, Alzheimer's disease, mild cognitive impairment, chemotherapy-induced cognitive dysfunction, Down syndrome, autism spectrum disorders, hearing loss, tinnitus, spinocerebellar ataxia, amyotrophic lateral sclerosis, multiple sclerosis, Huntington's disease, stroke, radiation therapy, chronic stress, abuse of neuro-active drugs, such as alcohol, opiates, methamphetamine, phencyclidine and cocaine.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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