CECCARELLI, Simona M. M,JAGASIA, Ravi,JAKOB-ROETNE, Roland -,PETERS, Jens-Uwe -,WICHMANN, Juergen,於爾根.維希曼,西蒙娜.,.切卡雷利,拉維.姚高希亞,羅蘭.雅各布-勒特,延斯-烏韋.彼得斯,於爾根.維希曼
申请号:
HK16104541.8
公开号:
HK1216749A
申请日:
2016.04.20
申请国别(地区):
HK
年份:
2016
代理人:
摘要:
The present invention relates to compounds of general formula I wherein R1, R2, R3 and R4 are as defined herein which maybe used for the treatment of schizophrenia, obsessive-compulsive personality disorder, major depression, bipolar disorders, anxiety disorders, normal aging, epilepsy, retinal degeneration, traumatic brain injury, spinal cord injury, post-traumatic stress disorder, panic disorder, Parkinson's disease, dementia, Alzheimer's disease, cognitive impairment, chemotherapy-induced cognitive dysfunction (“chemobrain”), Down syndrome, autism spectrum disorders, hearing loss, tinnitus, spinocerebellar ataxia, amyotrophic lateral sclerosis, multiple sclerosis, Huntington's disease, stroke, and disturbances due to radiation therapy, chronic stress, optic neuropathy or macular degeneration, or abuse of neuro-active drugs, selected from alcohol, opiates, methamphetamine, phencyclidine and cocaine.