The present invention relates to a compound of the general formula (II) or a salt or solvate thereof, as well as medical uses involving them, wherein A1 is selected from the group consisting of N and C-R8 A2 is selected from the group consisting of N and C-R3, A3 is selected from the group consisting of N and C-R9 A4 and A5 and A6 are independently selected from the group consisting of N and C-R1 R1 is selected from the group consisting of hydrogen, (C1-C3)alkyl, halogen, (C1-C3)alkoxy, and (C1-C3)haloalkyl R2 is selected from the group consisting of hydrogen, halogen, and (C1-C3)alkyl R3 is selected from the group consisting of hydrogen, (C1-C3)alkyl, NR4R5, (C1-C3)alkyl- NR4R5, and cyano, wherein R4 and R5 are independently selected from the group consisting of hydrogen, (C3-C5)cycloalkyl, (C3-C5)heterocycloalkyl and (C1-C3)alkyl, or R4 and R5 together with the nitrogen atom to which they are attached form a 5- to 7-membered heterocyclic ring optionally comprising in addition to the aforementioned nitrogen atom a further heteroatom group selected from the group consisting of O and NR6, wherein R6 is selected from the group consisting of hydrogen, methyl, acetyl and formyl Y is selected from the group consisting of O and S R8 is selected from the group consisting of (C1-C4)alkyl, (C3-C5)cycloalkyl and (C3-C5)heterocycloalkyl and R9 is selected from the group consisting of hydrogen, (C1-C3)alkyl and (C1-C3)alkoxy wherein certain particular compounds are excluded py proviso, and methods for producing such compounds.Cette invention concerne un composé de formule générale (II) ou un sel ou un solvate de celui-ci, ainsi que des utilisations médicales les impliquant, où A1 est choisi dans le groupe constitué par N et C-R8 A2 est choisi dans le groupe constitué par N et C-R3, A3 est choisi dans le groupe constitué par N et C-R9 A4 et A5 et A6 sont indépendamment choisis dans le groupe constitué par N et C-R1 R1est choisi dans le groupe constitué par un atome dhydrogène, u
