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DERIVES 5-[(PIPERAZINE-1-YL) -3-OXO-PROPYL]-IMIDAZOLIDINE -2,4-DIONE COMME INHIBITEURS D'ADAMTS POUR LE TRAITEMENT DE L'ARTHROSE
专利权人:
LES LABORATOIRES SERVIER;GALAPAGOS NV
发明人:
BREBION, FRANCK LAURENT,ALVEY, LUKE JONATHAN,AMANTINI, DAVID,DEPREZ, PIERRE MARC MARIE JOSEPH,GOSMINI, ROMAIN LUC MARIE,JARY, HELENE MARIE,PEIXOTO, CHRISTOPHE,VARIN, MARIE LAURENCE CLAIRE,DE CEUNINCK,
申请号:
CA2971110
公开号:
CA2971110A1
申请日:
2015.12.18
申请国别(地区):
CA
年份:
2016
代理人:
摘要:
The present invention discloses compounds according to Formula (I), wherein R, R2, R3a, R3b, and Cy are as defined herein. The present invention discloses compounds inhibiting ADAMTS, methods for their production, pharmaceutical compositions comprising the same and methods for the prophylaxis and/or treatment of inflammatory conditions and/or diseases involving degradation of cartilage and/or disruption of cartilage homeostasis.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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