composting, method for concentrating chitosan-nucleic acid polyplexes, concentrated dispersion of chitosan-nucleic acid polyplexes, pharmaceutical compounding, and method for latering the chitosan-nucleic acid polyplexe diameter

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专利权人:

Engene; inc

发明人:

Anthony Cheung,Carlos Fleet,Eric C. Hsu,Jun Gao

申请号：

BRPI0817725

公开号：

BRPI0817725A2

申请日:

2008.09.26

申请国别(地区):

BR

年份:

2017

代理人:

摘要：

The invention provides highly concentrated chitosan-nucleic acid polyplex compositions and dispersions, and methods for producing the compositions and dispersions. Methods of mixing the chitosan-nucleic acid polyplexes include an inline mixing of chitosan solution and nucleic acid solution, followed by further concentrating the dispersion of chitosan-nucleic acid polyplexes, optionally with an aggregation inhibitor. Further provided are methods for altering the diameter of chitosan-nucleic acid polyplexes.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/