LACHER, MARKUS DANIEL,WAGNER, JOSEPH PAUL,WISEMAN, CHARLES LOUIS,WILLIAMS, WILLIAM VALENTINE
申请号:
CA3015080
公开号:
CA3015080A1
申请日:
2017.02.27
申请国别(地区):
CA
年份:
2017
代理人:
摘要:
The present invention provides a modified human cancer cell comprising a recombinant polynucleotide encoding an allele of a human leukocyte antigen gene. The present invention also provides methods for selecting a whole-cell cancer vaccine for a subject having cancer and methods of treating cancer using whole-cell cancer vaccines of the present invention. In addition, the present invention provides a method of determining the HER2 status of a cell. Compositions and kits are also provided herein.