Lacher, Markus Daniel,Wagner, Joseph Paul,Wiseman, Charles Louis,Williams, William Valentine
申请号:
AU2017224232
公开号:
AU2017224232A1
申请日:
2017.02.27
申请国别(地区):
AU
年份:
2018
代理人:
摘要:
The present invention provides a modified human cancer cell comprising a recombinant polynucleotide encoding an allele of a human leukocyte antigen gene. The present invention also provides methods for selecting a whole-cell cancer vaccine for a subject having cancer and methods of treating cancer using whole-cell cancer vaccines of the present invention. In addition, the present invention provides a method of determining the HER2 status of a cell. Compositions and kits are also provided herein.