KHUSIAL, PERMANAN RAAJ,SANTHANAM, UMA,LYGA, JOHN W.
申请号:
PL11853582
公开号:
PL2658537T3
申请日:
2011.11.21
申请国别(地区):
PL
年份:
2015
代理人:
摘要:
Methods for preventing, ameliorating, or reducing dermatological signs of aging are provided which employ active agents that suppress or down-regulate microRNA expression in dermal fibroblast, resulting in enhanced production of collagen, elastin and/or fibrillin in the skin. Also provided are methods for screening for activity against specific microRNAs and the methods of using active agents identified by the screening protocol in the treatment of skin.