MAX-DELBRUCK-CENTRUM FUR MOLEKULARE MEDIZIN;BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
发明人:
SCHUNCK, WOLF-HAGEN,MULLER, DOMINIK,FISCHER, ROBERT,WALLUKAT, GERD,KONKEL, ANNE,FALCK, JOHN RUSSELL
申请号:
CA2934964
公开号:
CA2934964A1
申请日:
2015.01.21
申请国别(地区):
CA
年份:
2015
代理人:
摘要:
The present invention relates to compounds according to general formula (I) which are analogues of epoxymetabolites produced by cytochrome P450 (CYP) enzymes from omega-3 (n-3) polyunsaturated fatty acids (PUFAs). The present invention further relates to compositions containing one or more of these compounds and to the use of these compounds or compositions for the treatment or prevention of conditions and diseases associated with inflammation, proliferation, hypertension, coagulation, immune function, pathologic angiogenesis, heart failure and cardiac arrhythmias.