BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM;MAX-DELBRÜCK-CENTRUM FÜR MOLEKULARE MEDIZIN
发明人:
WOLF-HAGEN SCHUNCK,DOMINIK MÜLLER,ROBERT FISCHER,GERD WALLUKAT,ANNE KONKEL,JOHN RUSSELL FALCK
申请号:
PT15702370
公开号:
PT3097076T
申请日:
2015.01.21
申请国别(地区):
PT
年份:
2019
代理人:
摘要:
The present invention relates to compounds according to general formula (I) which are analogues of epoxymetabolites produced by cytochrome P450 (CYP) enzymes from omega-3 (n-3) polyunsaturated fatty acids (PUFAs). The present invention further relates to compositions containing one or more of these compounds and to the use of these compounds or compositions for C the treatment or prevention of conditions and diseases associated with inflammation, proliferation, hypertension, coagulation, immune function, pathologic angiogenesis, heart failure and cardiac arrhythmias.