Venkateswaralu, Jasti,Rajendiran, Chinnapillai,Reddy, Nallamaddi Ravikumar,Connolly, Terrence Joseph,Ruchelman, Alexander L.,Eckert, Jeffrey,Frank, Anthony Joseph
申请号：
AU2013203283
公开号：
AU2013203283B2
申请日:
2013.02.20
申请国别(地区):
AU
年份:
2015
代理人:
摘要：
#$%^&*AU2013203283B220151126.pdf#####ABSTRACT PROCESSES FOR THE PREPARATION OF (S)-1-(3-ETHOXY-4METHOXYPHENYL)-2-METHANESULFONYLETHYLAMINE Provided herein are new processes for the preparation of aminosulfone intermediates for the synthesis of 2-[1-(3-ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4acetylaminoisoindoline-1,3-dione, which is useful for preventing or treating diseases or conditions related to an abnormally high level or activity of TNF-a. Further provided herein are processes for the commercial production of (S)- 1 -(3 -ethoxy-4-methoxyphenyl)-2methanesulfonylethylamine. - 41 ATI-2549224vl
