Pye, Philip,Ben Haim, Cyril,Conza, Matteo,Houpis, Ioannis Nicolaos
申请号:
AU2018204086
公开号:
AU2018204086A1
申请日:
2018.06.08
申请国别(地区):
AU
年份:
2018
代理人:
摘要:
#$%^&*AU2018204086A120180628.pdf#####Abstract 5 PROCESSES AND INTERMEDIATES FOR PREPARING A MEDICAMENT Disclosed is a process for the preparation of the following compounds: R2a 0 R/ N H2N N NC H2N N 10 where R', R" and R2a have the definitions in the description, as well as a process to prepare other intermediates that may be useful to synthesise downstream products, especially compounds that are useful as medicaments, for instance Bruton's tyrosine kinase (Btk) inhibitors such as ibrutinib. Also disclosed are other processes, other 15 intermediates and compounds per se.