LOW, PHILIP STEWART,VARGHESE, BINDU,VLAHOV, IONTCHO RADOSLAVOV
申请号：
CA2592302
公开号：
CA2592302C
申请日:
2005.12.23
申请国别(地区):
CA
年份:
2013
代理人:
摘要：
The invention relates to compositions and methods to diagnose/monitor, using positron emission tomography, pathogenic disease states wherein the pathogenic cells uniquely express, preferentially express, or overexpress vitamin receptors. In an illustrative embodiment, vitamins, or analogs thereof, conjugated to a radiophore are used to diagnose/monitor disease states extra-corporeally using positron emission tomography. The disease states that can be diagnosed/monitored in accordance with the invention are cancer and disease states involving activated macrophages, such as disease states involving an inflammatory response.
