System of the present invention closes a kind of secondary universe Lactobacillus casei strain of what and prepares the purposes for improving the composition of enterobacteriaceae phase with what, wherein the pair universe Lactobacillus casei strain is pair universe Lactobacillus casei strain Yb (Lactobacillus paracaseiYb), and deposit number is BCRC 910415. The composition that pair universe Lactobacillus casei strain of the present invention is prepared has the effect for improving enterobacteriaceae phase.本發明係關於一種副乾酪乳酸桿菌株用於製備改善腸道菌相之組合物的用途,其中該副乾酪乳酸桿菌株為副乾酪乳酸桿菌株Yb (Lactobacillus paracaseiYb),寄存編號為BCRC 910415。本發明所述之副乾酪乳酸桿菌株製備而得之組合物具有改善腸道菌相之效果。