MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR

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专利权人:

VERTEX PHARMACEUTICALS INCORPORATED

发明人:

BINCH, HAYLEY,GROOTENHUIS, PETER,HADIDA RUAH, SARA,ZHOU, JINGLAN

申请号：

NZ58141908

公开号：

NZ581419A

申请日:

2008.05.23

申请国别(地区):

NZ

年份:

2012

代理人:

摘要：

The disclosure relates to modulators of ATP-Binding Cassette ("ABC") transporters or fragments thereof, including Cystic Fibrosis Transmembrane Conductance Regulator (CFTR), compositions thereof, and methods therewith. The disclosure particularly thieno-pyridine derivatives of represented by formula (I) or formula (II) and pharmaceutically acceptable salts thereof, wherein the variables are as defined in the specification.

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