Formulations de l'agomélatine, comprenant l'agomélatine sous forme des co-cristals

• 收藏
• 分享

专利权人:

Zentiva; K.S.

发明人:

申请号：

EP13002930.9

公开号：

EP2810656A1

申请日:

2013.06.06

申请国别(地区):

EP

年份:

2014

代理人:

摘要：

A pharmaceutical formulation of agomelatine for oral use, comprising- agomelatine in the form of agomelatine co-crystals with organic acids and- pharmaceutically acceptable excipients,in which- the agomelatine co-crystals are used in the form of pre-blend of the agomelatine co-crystals with a glidant,- the ratio of the agomelatine co-crystals to the glidant in the pre-blend is lower than or equal to 30 : 1, and- the free-water content in the used pharmaceutically acceptable excipients is lower than or equal to 7% w/w.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/