Provided are dermatological medical devices and methods comprising a distal end for positioning at a region proximal a target therapeutic region of tissue, an output port at the distal end, an energy source that generates optical energy, which is output from the output port to the target therapeutic region of tissue, and a microcontroller that processes replenishment data that controls an operation parameter of the device. The device is activated for performing a treatment operation in response to a receipt and processing of the replenishment data.