OMOTO Kiyoyuki,OMOTO Kiyoyuki,OWEN Robert McKenzie,OWEN Robert McKenzie,PRYDE David Cameron,PRYDE David Cameron,WATSON Christine Anne Louise,WATSON Christine Anne Louise,TAKEUCHI Mifune,TAKEUCHI Mifun
申请号:
SI201330382
公开号:
SI2938615T1
申请日:
2013.12.04
申请国别(地区):
SI
年份:
2017
代理人:
摘要:
The present invention relates to imidazopyridazine derivatives. More particularly, it relates to 4-(biphenyl-3-yl)-7H-imidazo[4,5-c]pyridazine derivatives of formula (I): and pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R4 and R5 are as defined in the description. The imidazopyridazine derivatives of the present invention modulate the activity of the GABAA receptor. They are useful in the treatment of a number of conditions, including pain.