Robert McKenzie Owen,David Cameron Pryde,Mifune Takeuchi,Christine Anne Louise Watson
申请号:
US15316552
公开号:
US09802945B2
申请日:
2015.06.03
申请国别(地区):
US
年份:
2017
代理人:
摘要:
The present invention relates to imidazopyridazine derivatives. More particularly, it relates to 4-(biphenyl-3-yl)-7H-imidazo[4,5-c]pyridazine derivatives of formula (I):and pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R4, R5 and R6 are as defined in the description. The imidazopyridazine derivatives of the present invention modulate the activity of the GABAA receptor. They are useful in the treatment of a number of conditions, including pain.