A method for imparting an article or a hygiene product with antimicrobial activity includes a step of applying an antimicrobial agent including an antimicrobial polyaminosilane to the article or the hygiene product. The antimicrobial polyaminosilane is prepared by subjecting an aminosilane monomer to a hydrolysis and condensation reaction. The antimicrobial polyaminosilane thus prepared is free of halide ions.本發明提供一種抗菌、防霉的表面塗料，用於塗覆於一基材的表面，該表面塗料包含：一由氨基矽烷氧化合物之單體經水解反應及縮合反應的其中至少一種反應聚合而得的抗菌防霉劑。此外，本發明還提供一種抗菌、防霉的表面塗料的製作方法，包含以下步驟：步驟(a)，準備至少一種氨基矽烷氧化合物之單體；及步驟(b)，將該至少一種氨基矽烷氧化合物之單體進行水解反應及縮合反應的其中至少一種，即得一抗菌防霉劑。
