Tim West,Diljeet S. Athwal,Timothy D. Jones,Francis J. Carr,Robert George Edward Holgate
申请号：
US15257086
公开号：
US09957317B2
申请日:
2016.09.06
申请国别(地区):
US
年份:
2018
代理人:
摘要：
Provided herein is an isolated antibody or antigen-binding fragment that specifically binds tau, the antibody or fragment comprising a heavy chain variable (VH) region and a light chain variable (VL) region having amino acid sequences set forth herein. Also provided are methods of preventing or treating a tauopathy in a subject, comprising administering to a human in need of therapy for a tauopathy with one or more antibodies or fragments as described herein, wherein the antibodies or antigen-binding fragment are administered under conditions and in an amount effective to prevent or treat the tauopathy.
