WEST, TIM,ATHWAL, DILJEET S.,JONES, TIMOTHY D.,CARR, FRANCIS J.,HOLGATE, ROBERT GEORGE EDWARD
申请号:
CA2953809
公开号:
CA2953809A1
申请日:
2015.06.26
申请国别(地区):
CA
年份:
2015
代理人:
摘要:
Provided herein is an isolated antibody or antigen-binding fragment that specifically binds tau, the antibody or fragment comprising a heavy chain variable (VH) region and a light chain variable (VL) region having amino acid sequences set forth herein. Also provided are methods of preventing or treating a tauopathy in a subject, comprising administering to a human in need of therapy for a tauopathy with one or more antibodies or fragments as described herein, wherein the antibodies or antigen-binding fragment are administered under conditions and in an amount effective to prevent or treat the tauopathy.