Method to induce and expand therapeutic alloantigen-specific human regulatory T cells in large-scale

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专利权人:

Wenwei Tu

发明人:

Wenwei Tu,Yu-Lung Lau,David Bram Lewis

申请号：

US14152269

公开号：

US09480715B2

申请日:

2014.01.10

申请国别(地区):

US

年份:

2016

代理人:

摘要：

Methods for inducing, expanding, and/or generating alloantigen-specific regulatory T cells. Alloantigen-specific regulatory T cells can be induced, expanded, and/or generated from naive CD4+CD25− T cells by using CD40-activated B cells. The regulatory T cells can be human T cells. In one embodiment, the alloantigen-specific human regulatory T cells can be CD4highCD25+Foxp3+ regulatory T cells.

来源网站：

中国工程科技知识中心

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http://www.ckcest.cn/home/