The present invention relates to an external medicine application mechanism comprising a support rod and a coating body coupled to an upper portion of a support rod, wherein the coating body comprises a first inclined surface portion provided at one side of the connection portion so as to be inclined with respect to a horizontal plane, And a second inclined surface portion inclined with respect to a horizontal plane on the other side of the connection portion in a direction opposite to the first inclined surface portion, Wherein the first inclined surface portion is provided with a coating plate made of a silicone material on the front surface thereof and the second inclined surface portion is provided with a protruding portion protruding from the center of the inner portion and a protruding portion protruding from the center of the protruding portion, And a fastening clip fixed to the fastening groove, wherein the fastening sleeve has a coil spring inside, And the upper end of the support rod is provided with a coupling protrusion which can be fitted and fixed to the fixing groove at a position corresponding to a plurality of fixing grooves formed on the bottom surface of the coupling portion, And the external medicine applying mechanism is formed by projecting the external medicine. According to another aspect of the present invention, there is provided an external medicine application device including a plurality of fitting protrusions on a back surface thereof, the fitting protrusions being engageable with a plurality of fitting grooves formed on a front surface of the first inclined surface portion. Further, according to the present invention, there is provided an external medicine application mechanism in which a grip portion is provided below the support rod and a plurality of grooves for finger placement are provided in the grip portion. Therefore, according to the present invention, it is possible to provide an external medicine application mechanism that i