Vaccine vectors and methods of enhancing immune responses

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专利权人:

THE TEXAS A&M UNIVERSITY SYSTEM;THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS

发明人:

Berghman, Luc,Bottje, Walter,Hargis, Billy,Layton, Sherryll

申请号：

AU2011207331

公开号：

AU2011207331B2

申请日:

2011.01.21

申请国别(地区):

AU

年份:

2014

代理人:

摘要：

Provided herein are vaccine vectors including an antigenic polypeptide and an HMGB 1 polypeptide present on the surface of the vaccine vector. Compositions comprising the vaccine vectors are also provided and include a pharmaceutically acceptable carrier, suitably a carrier for oral or nasal administration. Also provided are methods of enhancing immune responses, in particular antibody immune response and suitably an IgA response, by administering the vaccine vectors or compositions disclosed herein to a subject.

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