Disclosed is a stable crystal of 1-(2-cyano-2-deoxy-²-D-arabinofuranosyl)cytosine monohydrochloride. There is provided a crystal of l-(2-cyano-2-deoxy-²-D-arabinofuranosyl)cytosine monohydrochloride having characteristic peaks at 13.7°, 15.7°, 16.0°, 18.6°, 20.3°, and 22.7° as diffraction angles (2¸ ± 0.1°) measured by powder X-ray diffraction, and having a melting point of 192°C to 197°C..