NOVEL STABLE CRYSTAL OF 1-(2'-CYANO-2'-DEOXY-&beta；-D-ARABINOFURANOSYL)CYTOSINE MONOHYDROCHLORIDE

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专利权人:

데루타-후라이 화마 가부시키가이샤;DELTA-FLY PHARMA; INC.;DELTA-FLY PHARMA, INC.

发明人:

WATANABE SHOTARO,와타나베 쇼타로,HATAKEYAMA TAKAHIRO,하타케야마 다카히로

申请号：

KR1020117027019

公开号：

KR1020120022940A

申请日:

2010.05.14

申请国别(地区):

KR

年份:

2012

代理人:

摘要：

Disclosed is a stable crystal of 1-(2'-cyano-2'-deoxy-²-D-arabinofuranosyl)cytosine monohydrochloride. There is provided a crystal of l-(2'-cyano-2'-deoxy-²-D-arabinofuranosyl)cytosine monohydrochloride having characteristic peaks at 13.7°, 15.7°, 16.0°, 18.6°, 20.3°, and 22.7° as diffraction angles (2¸ ± 0.1°) measured by powder X-ray diffraction, and having a melting point of 192°C to 197°C..1-(2'-시아노-2'-데옥시-β-D-아라비노푸라노실)시토신·1염산염의 안정형 결정을 얻는 것.분말 X 선 회절에 의한 회절각 (2θ±0.1°) 으로서, 13.7°, 15.7°, 16.0°, 18.6°, 20.3°및 22.7°에서 특징적인 피크를 확인하고, 융점이 192 ～ 197 ℃ 인 1-(2'-시아노-2'-데옥시-β-D-아라비노푸라노실)시토신·1염산염의 결정.

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中国工程科技知识中心

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