SEO, MI JA;서미자;재단법인 한국한방산업진흥원;INSTITUTE FOR KOREA TRADITIONAL MEDICAL INDUSTRY
发明人:
SON, JUN HO,손준호,PARK, TAE SOON,박태순,JUNG, MI SONG,정미송,KIM, HUI JEONG,김희정,HWANG, JU YOUNG,황주영,KIM, DONG HEE,김동희,HWANG, EUN YOUNG,황은영
申请号：
KR1020100093236
公开号：
KR1020120031696A
申请日:
2010.09.27
申请国别(地区):
KR
年份:
2012
代理人:
摘要：
PURPOSE: A composition containing complex crude drug extract is provided to suppress tyrosinase and melanogenesis and to ensure excellent skin whitening. CONSTITUTION: An external use pharmaceutical composition for skin whitening contains 0.1-50wt% of Rhei Rhizoma, Cinnamomi Ramulus, Glycyrrhizae Radix, and Persicae semen. The extract is isolated using water, ethanol, methanol, propanol, butanol, acetone, ethyl acetate, hexane, butylene glycol, propylene glycol, hydrous butylene glycol, hydrous propylene glycol, or hydrous glycerin. The pharmaceutical composition is manufactured in the form of a cream, gel, patch, spray, ointment, lotion, liniment, paste, or cataplasma.본 발명은 복합생약 추출물을 유효성분으로 함유하는 조성물에 관한 것으로, 구체적으로 우수한 티로시나제 저해활성을 나타내고, B16F10 melanoma 세포 내 실험에서 멜라닌 합성 저해 활성을 나타내는바 본 발명의 복합생약 추출물은 미백 효과를 갖는 피부외용 약학조성물 및 화장료 조성물로 유용하게 이용될 수 있다.
