抗Aおよび抗B抗体、ならびに多反応性IgGが減少した免疫グロブリンG(IgG)濃縮物
- 专利权人:
- 发明人:
- 申请号:
- JP20080548014
- 公开号:
- JP5726403(B2)
- 申请日:
- 2006.12.26
- 申请国别(地区):
- 日本
- 年份:
- 2015
- 代理人:
- 摘要:
Immunoglobulin G (IgG) concentrate for therapeutic use, comprises anti-A and anti-B antibodies compliant with a negative result in the indirect Coombs test in vitro. An independent claim is included for obtaining the IgG concentrate comprising preparing an IgG concentrate by ethanolic fractionation and/or chromatographic separation, in association with a viral inactivation, immunoaffinity chromatography by percolation of the IgG concentrate on a support mixture of which matrices are grafted with oligosaccharide groups antigenically similar to blood groups A and B, and filtering for elimination of virus and/or particles of size higher than 20 nm. ACTIVITY : Antimicrobial; Immunosuppressive. MECHANISM OF ACTION : None given.
- 来源网站:
- 中国工程科技知识中心