Jay Gregory Calvert,Robert G. Ankenbauer,Jacqueline Gayle Marx,Douglas S. Pearce,Marcia L. Keith
申请号:
US16530019
公开号:
US20190351045A1
申请日:
2019.08.02
申请国别(地区):
US
年份:
2019
代理人:
摘要:
The invention provides isolated polynucleotide molecules that comprise a DNA sequence encoding an infectious RNA sequence encoding a genetically-modified North American PRRS virus, methods to make it and related polypeptides, polynucleotides, and various components. Vaccines comprising the genetically modified virus and polynucleotides and a diagnostic kit to distinguish between naturally infected and vaccinated animals are also provided.