CALVERT, JAY GREGORY,ANKENBAUER, ROBERT G.,MARX, JACQUELINE GAYLE,PEARCE, DOUGLAS S.,KEITH, MARCIA L.
申请号:
PH12014502534
公开号:
PH12014502534A1
申请日:
2014.11.13
申请国别(地区):
PH
年份:
2015
代理人:
摘要:
The invention provides isolated polynucleotide molecules that comprise a DNA sequence encoding an infectious RNA sequence encoding a genetically-modified North American PRRS virus, methods to make it and related polypeptides, polynucleotides, and various components. Vaccines comprising the genetically modified virus and polynucleotides and a diagnostic kit to distinguish between naturally infected and vaccinated animals are also provided.