The present invention relates to an oral preparation containing zoledronic acid, which reduces enteric injuries and improves bioavailability. More particularly, the present invention relates to an oral preparation having an enteric coating, which comprises zoledronic acid and the pharmaceutically acceptable salts thereof, and which has a core, the pH level of which is 3.5 to 7.La présente invention concerne une préparation orale contenant de lacide zolédronique, qui réduit des lésions entériques et améliore la biodisponibilité. Plus particulièrement, la présente invention concerne une préparation orale ayant un enrobage entérique, qui comprend de lacide zolédronique et les sels pharmaceutiquement acceptables de celui-ci, et qui présente un noyau, dont le niveau de pH est de 3,5 à 7.본 발명은 장내 손상을 감소시키면서도 생체이용률이 개선된 졸레드론산 함유 경구 제제에 관한 것으로, 보다 구체적으로, 졸레드론산 및 약학적으로 허용되는 이의 염을 포함하고 코어의 pH가 3.5 내지 7인 장용코팅된 경구용 제제에 관한 것이다.
