Nicole Kallewaard-Lelay,Qing Zhu,Ebony Benjamin,Leslie Wachter,Andy Yuan,Josephine Mary McAuliffe,Davide Corti,Antonio Lanzavecchia
申请号:
US16361653
公开号:
US10519221B2
申请日:
2019.03.22
申请国别(地区):
US
年份:
2019
代理人:
摘要:
The invention relates to antibodies and antigen binding fragments thereof that are capable of binding to influenza B virus hemagglutinin (HA) and neutralizing influenza B virus in two phylogenetically distinct lineages. In one embodiment, the antibody or antigen binding fragment is capable of binding to influenza B virus hemagglutinin and neutralizing influenza B virus in Yamagata and Victoria lineages.