FIELD: medicine.SUBSTANCE: invention refers to medicine, namely to dermatology. To predict the deterioration probability of the clinical course of eczema, the progression into erythroderma, an integrated assessment of a pathoigenetic significance of the detected risk factors is made. What is determined is a prognostic coefficient (PC) for such criteria, as: sex age petrochemical workers agricultural workers construction workers drivers office staff hyper insolation adverse agricultural labour conditions (pesticide and fertiliser contact) petroleum contact construction material contact drug abuse pockets of chronic bacterial and/or mycotic infections frequent acute respiratory viral infections chronic gastrointestinal and/or hepatic diseases chronic respiratory infections chronic otorhinolaryngological organs disturbed liver detoxification liver metabolic disturbance immunoregulatory index decrease stimulation index decrease cytotoxic index decrease circulating immune complex increase average immunoglobulin increase blood skin antigen antitissue autoantibody increase leukocyte migration inhibition index increase. If a factor is absent, the related PC is considered to be zero. The derived PCs are summed up. The PC value is 2.64 to 10.23 enables predicting the low deterioration probability of the clinical course of eczema and the favourable prognosis of the disease implying no progression of the local form of the disease into the disseminated form. The derived PC falling within the range of 10.24 to 30.24 shows the medium deterioration probability of the clinical course of eczema and the possible progression of the local form of the disease into the disseminated form, with the relatively favourable prognosis with no developing erythroderma. The derived total PC within the range of 30.25 to 50.25 and higher provides the high deterioration probability of the clinical course of the disease, and the unfavourable prognosis, and the potential progression into erythroderma.EF
