СПОСОБ ПРОГНОЗИРОВАНИЯ ВЕРОЯТНОСТИ УХУДШЕНИЯ КЛИНИЧЕСКОГО ТЕЧЕНИЯ ПСОРИАЗА, ПЕРЕХОДА ЕГО В ЭРИТРОДЕРМИЮ С УЧЕТОМ ИММУНОЛОГИЧЕСКИХ ПОКАЗАТЕЛЕЙ, ДЕТОКСИКАЦИОННОЙ И МЕТАБОЛИЧЕСКОЙ ФУНКЦИИ ПЕЧЕНИ
FIELD: medicine.SUBSTANCE: invention refers to medicine, namely to dermatology. To predict the deterioration probability of the clinical course of psoriasis, the progression into erythroderma, an integrated assessment of a pathoigenetic significance of the detected risk factors promoting the deterioration is made. What is determined is a prognostic coefficient (PC) for such criteria, as: sex age petrochemical workers agricultural workers construction workers drivers office staff hyper insolation adverse agricultural labour conditions (pesticide and fertiliser contact) petroleum contact construction material contact drug abuse pockets of chronic bacterial and/or mycotic infections frequent acute respiratory viral infections chronic gastrointestinal and/or hepatic diseases chronic pulmonary diseases chronic respiratory infections chronic otorhinolaryngological organs disturbed liver detoxification liver metabolic disturbance circulating immune complex increase immunoglobulin increase immunoregulatory index decrease stimulation index decrease cytotoxic index decrease antitissue autoantibody increase blood skin antigen leukocyte migration inhibition index increase. If a factor is absent, the related PC is considered to be zero. The derived PCs are summed up. If PC is 5.64-16.24, the low deterioration probability of the clinical course of psoriasis and the favourable prognosis the PC value being 16.25-26.85 shows the medium deterioration probability and the relatively favourable prognosis the value of 26.86-37.86 and more provides the high probability and the unfavourable prognosis, and the potential progression into erythroderma.EFFECT: method enables predicting the deterioration probability of the clinical course of psoriasis, the progression into erythroderma.3 ex, 4 tblИзобретение относится к области медицины, а именно к дерматологии. Для прогнозирования вероятности ухудшения клинического течения псориаза, перехода его в эритродермию, проводят интегрированную оценку
