MIHOV GEORGE,DRAAISMA GUY,SILVESTRE DI SILVANA RENSINA ANTONNIETTA,HANDELS TRISTAN
申请号:
IN201717016958
公开号:
IN201717016958A
申请日:
2017.05.15
申请国别(地区):
IN
年份:
2017
代理人:
摘要:
The present invention relates to a drug delivery system comprising a core and a shell in which the core comprises a hydrolytically degradable polymer X which polymer backbone comprises pendant ester and acid functionalities and in which the shell comprises a hydrolytic degradable polymer Y. The hydrolytic degradable polymers X and Y are different polymers. Polymer X further comprises amino acids in the polymer backbone and degrades via zero order degradation kinetics for a period of at least 3 months. Polymer Y degrades via auto acceleration degradation kinetics.