Mihov, George,Draaisma, Guy,Silvestre, Di Silvana Rensina Antonnietta,Handels, Tristan
申请号：
AU2015366355
公开号：
AU2015366355A1
申请日:
2015.12.18
申请国别(地区):
AU
年份:
2017
代理人:
摘要：
The present invention relates to a drug delivery system comprising a core and a shell in which the core comprises a hydrolytically degradable polymer X which polymer backbone comprises pendant ester and acid functionalities and in which the shell comprises a hydrolytic degradable polymer Y. The hydrolytic degradable polymers X and Y are different polymers. Polymer X further comprises amino-acids in the polymer backbone and degrades via zero order degradation kinetics for a period of at least 3 months. Polymer Y degrades via auto-acceleration degradation kinetics.
