An embodiment includes analyzing a body part perfused with a contrast agent, which has been pre-administered as a bolus to circulate through the body-part with at least a first passage during an analysis interval. The analyzing includes providing at least one input signal indicative of a response to an interrogation signal of a corresponding location of the body part during the analysis interval, and fitting each input signal over the analysis interval by an instance of a combined bolus function of time, based on a combination of a first simple bolus function of time modeling the first passage of the contrast agent and at least one second simple bolus function of time each one modeling a corresponding second passage of the contrast agent.
