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N-pyrimidin-4-yl-3-amino-pyrrolo[3,4-c]pyrazole derivatives as PKC kinase inhibitors
专利权人:
Stephanie Anne Scales;Chunfeng Yin;Hui Li;Min Teng;Seiji Nukui
发明人:
Hui Li,Seiji Nukui,Stephanie Anne Scales,Min Teng,Chunfeng Yin
申请号:
US12523965
公开号:
US08183255B2
申请日:
2008.02.04
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The present invention relates to compounds and pharmaceutically acceptable salts of Formulas A and B: (A) and (B) wherein A, B, R1, R2, R3, R4, R5, R6, R7, R8, R9 and R10 are as defined above. The invention further relates to pharmaceutical compositions comprising the compounds and pharmaceutically acceptable salts and to methods of treating diabetes mellitus and its complications, cancer, ischemia, inflammation, central nervous system disorders, cardiovascular disease, Alzheimer's disease and dermatological disease pression, virus diseases, inflammatory disorders, or diseases in which the liver is a target organ.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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