Methods and products for modulating microbiota composition for improving the efficacy of a cancer treatment with an immune checkpoint blocker

• 收藏
• 分享

专利权人:

Institut Gustave Roussy;Institut National de la Sante et de la Recherche Medicale (INSERM);Universite Paris-Sud;Institut National de la Recherche Agronomique (INRA)

发明人:

Zitvogel, Laurence,Vetizou, Marie,Lepage, Patricia

申请号：

AU2015334468

公开号：

AU2015334468A1

申请日:

2015.10.23

申请国别(地区):

AU

年份:

2017

代理人:

摘要：

The present invention relates to the role of the microbiota in the efficacy of cancer treatments with a drug blocking an. immune checkpoint and provides methods and probiotics to improve the efficacy of such a treatment in patients in need thereof. More particularly, the invention pertains to the use of vancomycin or penicillin to modulate the gut microbiota to potentiate the anticancer effects of anti-CTLA4 molecules.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/