MCDONNELL, PETER J.,KHAN, YASIN A.,LAI, SAMUEL K.,KASHIWABUCHI, RENATA T.,BEHRENS, ASHLEY,HANES, JUSTIN S.
申请号:
CA2791278
公开号:
CA2791278C
申请日:
2011.02.25
申请国别(地区):
CA
年份:
2015
代理人:
摘要:
Compositions and methods for treating eye disorders by administering a drug delivery system into an eye compartment of the patient, wherein the drug delivery system contains a particle containing a core a coating associated with the particle, wherein the wherein the coating is covalently or non-covalently associated with the particle and presents a hydrophilic region to the environment around the particle and a therapeutic agent are disclosed. The eye compartment can exhibit reduced inflammation or IOP after administration of the drug delivery systems to a patient than if a drug delivery system including an uncoated particle were administered to the patient.