Peter J. McDonnell,Yasin A. Khan,Samuel K. Lai,Renata T. Kashiwabuchi,Ashley Behrens,Justin S. Hanes
申请号：
US16502359
公开号：
US20190321297A1
申请日:
2019.07.03
申请国别(地区):
US
年份:
2019
代理人:
摘要：
Compositions and methods for treating eye disorders by administering a drug delivery system into an eye compartment of the patient, wherein the drug delivery system contains a particle containing a core； a coating associated with the particle, wherein the coating is covalently or non-covalently associated with the particle and presents a hydrophilic region to the environment around the particle； and a therapeutic agent are disclosed. The eye compartment can exhibit reduced inflammation or TOP after administration of the drug delivery systems to a patient than if a drug delivery system including an uncoated particle were administered to the patient.
