LEE, WEI HAN,WANG, NAN-HSUAN,CHANG, CHUNG-HAO,HSIEH, YIH-HUANG,WANG, CHENG-CHI,LIN, YU-HSIN,LIN, YU-CHEN,CHEN, I-JU,YU, CHENG DER TONY
申请号:
CA3044471
公开号:
CA3044471A1
申请日:
2014.01.06
申请国别(地区):
CA
年份:
2014
代理人:
摘要:
The present invention provides vaccines comprising carbohydrate antigenconjugated to a diphtheria toxin (DT) as a carrier protein, wherein the ratioofthe number of carbohydrate antigen molecule to the carrier protein moleculeis higher than 5:1. Also disclosed herein is a novel saponin adjuvant andmethods to inhibit cancer cells, by administering an effective amount of thevaccine disclose herein.