VACCINS A FORTE DENSITE EN ANTIGENES CARBOHYDRATES ET COMPORTANT UN ADJUVANT INEDIT A BASE DE SAPONINE

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专利权人:

INC.;OBI PHARMA

发明人:

YU, CHENG DER TONY,LEE, WEI HAN,WANG, NAN-HSUAN,CHANG, CHUNG-HAO,HSIEH, YIH-HUANG,WANG, CHENG-CHI,LIN, YU-HSIN,LIN, YU-CHEN,CHEN, I-JU

申请号：

CA2897084

公开号：

CA2897084C

申请日:

2014.01.06

申请国别(地区):

CA

年份:

2019

代理人:

摘要：

The present invention provides vaccines comprising carbohydrate antigen conjugated to a diphtheria toxin (DT) as a carrier protein, wherein the ratio of the number of carbohydrate antigen molecule to the carrier protein molecule is higher than 5:1. Also disclosed herein is a novel saponin adjuvant and methods to inhibit cancer cells, by administering an effective amount of the vaccine disclose herein.

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中国工程科技知识中心

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http://www.ckcest.cn/home/