BENNETT, Michael J.,BETANCORT, Juan M.,BOLOOR, Amogh,KANOUNI, Toufike A.,STAFFORD, Jeffrey A.,VEAL, James M.,WALLACE, Michael B.
申请号：
EP17786389
公开号：
EP3445750A4
申请日:
2017.04.14
申请国别(地区):
EP
年份:
2019
代理人:
摘要：
The present disclosure relates to substituted heterocyclic derivative therapeutic compounds, compositions comprising said compounds, and the use of said compounds and compositions for epigenetic regulation by inhibition of bromodomain-mediated recognition of acetyl lysine regions of proteins, such as histones. Said compositions and methods are useful for the treatment of diseases mediated by aberrant cell signalling, such as inflammatory disorders, cancer and neoplastic disease.
