PROBLEM TO BE SOLVED: To provide an artificial material capable of forming an artificial blood vessel having a similar mechanical property to a blood vessel of an organism, which is a hybrid type artificial blood vessel in which endothelial cells are multiplied on the inside surface.SOLUTION: A biocompatibility modifying gel material composition comprises a solution containing a saponified product of a vinyl acetate-diacetoneacrylamide copolymer and unmodified polyvinyl alcohol having a saponification degree of 98 mol% or higher. A biocompatibility modifying gel is formed by gelatinizing the biocompatibility modifying gel material.SELECTED DRAWING: None【課題】内側表面に内皮細胞を増殖させたハイブリッド型の人工血管であって力学的性質が生体の血管と近似した人工血管を、形成可能である人工材料を提供すること。【解決手段】酢酸ビニル-ジアセトンアクリルアミド共重合体の鹸化物、及びケン化度98モル%以上の未変性ポリビニルアルコールを含む溶液からなる生体適合修飾性ゲル材料組成物、及び該生体適合修飾性ゲル材料組成物がゲル化されてなる生体適合修飾性ゲル。【選択図】なし