GOEHRING, R. RICHARD,TAFESSE, LAYKEA,YAO, JIANGCHAO
申请号:
CA2813704
公开号:
CA2813704A1
申请日:
2011.10.05
申请国别(地区):
CA
年份:
2012
代理人:
摘要:
The invention relates to aryl substituted quinazolines of Formula I, and pharmaceutically acceptable salts, prodrugs, or solvates thereof, wherein G, A, and R1-R4 are defined as set forth in the specification. The invention is also directed to the use of compounds of Formula I to treat a disorder responsive to the blockade of sodium channels. Compounds of the present invention are especially useful for treating pain.